R-alpha-Lipoic acid sodium CAS 176110-81-9

R-alpha-Lipoic acid sodium CAS 176110-81-9

Identification
Properties
Safety Data
Specifications & Other Information
Links

Identification

CAS Number

176110-81-9

Name

R-alpha-Lipoic acid sodium

Synonyms

1,2-Dithiolane-3-pentanoic acid, sodium salt, (3R)- (1:1) [ACD/Index Name]
5-[(3R)-1,2-Dithiolan-3-yl]pentanoate de sodium [French] [ACD/IUPAC Name]
Natrium-5-[(3R)-1,2-dithiolan-3-yl]pentanoat [German] [ACD/IUPAC Name]
Sodium 5-[(3R)-1,2-dithiolan-3-yl]pentanoate [ACD/IUPAC Name]
176110-81-9 [RN]
2319-84-8 [RN]
Sodium (R)-5-(1,2-dithiolan-3-yl)pentanoate
Sodium thioctate
UNII-L9R2WBJ3BR

SMILES

C1CSS[[email protected]@H]1CCCCC(=O)[O-].[Na+]

StdInChI

InChI=1S/C8H14O2S2.Na/c9-8(10)4-2-1-3-7-5-6-11-12-7;/h7H,1-6H2,(H,9,10);/q;+1/p-1/t7-;/m1./s1

StdInChIKey

UUDFBRWLHZIIQX-OGFXRTJISA-M

Molecular Formula

C8H13NaO2S2

Molecular Weight

228.307

Properties

Appearance

Off white or pale yellow powder

Melting Point

240℃~250℃

Safety Data

WGK Germany

3

Specifications and Other Information of Our R-alpha-Lipoic acid sodium CAS 176110-81-9

Standard

Enterprise standard

Identification Methods

HNMR,HPLC

Assay by HPLC

99%min

Assay of R-alpha-Lipoic acid by HPLC

80%min

Specific Optical Rotation

+60°~+85°

Heavy Metals

10ppm max

Loss on Drying

3.0%max

Package

According to customer requirements to packaging

Storage

Under the room temperature and away from light

Application

Lipoic acid (LA), also known as alpha lipoic acid (ALA) and thioctic acid is an organosulfur compound which is widely used as a dietary supplement in some countries marketed as an antioxidant and is available as a pharmaceutical drug in other countries.

Alpha-Lipoic Acid bulk material available today is (R/S) or (+/-) Alpha Lipoic Acid (ALA), meaning it contains a 50/50 mixture of (R-Lipoic) and unnatural (S-Lipoic) Lipoic Acid. The S-Lipoic Acid form, which is not found anywhere in nature, is a byproduct of chemical synthesis. Research indicates that not only does the human body have difficulty absorbing this unnatural version, it may inhibit the most essential properties of the R-Lipoic Acid form!

The “R” form (R Lipoic) is considered the “eutomer” (the biologically superior form) of Alpha Lipoic Acid, since it is identical to that produced by the body. Research indicates R-Lipoic Acid is responsible for most of the beneficial effects attributed to ALA.

While R Lipoic Acid is the obvious choice over Alpha Lipoic Acid, pure R-Lipoic Acid in its “free-acid” form has two major drawbacks: stability and bioavailability. Without special processing, R-Lipoic Acid is highly unstable and difficult to absorb. In fact, pharmacokinetic data reveal that while Alpha Lipoic Acid has a very low absorption rate, unstabilized R-Lipoic Acid is absorbed even worse!

As one of the largest fine chemical developers globally, Watson solved the stability issue by bringing in two other derivates R(+)-Alpha Lipoic Acid Sodium CAS 176110-81-9 and R-alpha-Lipoic acid tromethamine salt CAS 14358-90-8, being one of the world’s largest purveyor of commercially produced stabilized R-Lipoic Acid materials.

You know check here to know more about our two products,

R-(+)-alpha-Lipoic acid CAS 1200-22-2: http://www.watson-int.com/r-alpha-lipoic-acid-cas-1200-22-2/

R-alpha-Lipoic acid tromethamine salt CAS 14358-90-8: http://www.watson-int.com/r-alpha-lipoic-acid-tromethamine-salt-cas-14358-90-8/

Links

This product is sold exclusively through our sales company Watson International Ltd, and please click the link below for details.
http://www.watson-int.com/r-alpha-lipoic-acid-sodium-cas-176110-81-9/