D-erythro-sphingosine-1-phosphate CAS 26993-30-6
Identification
CAS Number
26993-30-6
Name
D-erythro-sphingosine-1-phosphate; S1P
Synonyms
(4E)-2-Amino-3-hydroxy-4-octadecen-1-yl dihydrogen phosphate
[IUPAC name – generated by ACD/Name]
(4E)-2-Amino-3-hydroxy-4-octadecen-1-yldihydrogen-phosphat
(4E)-2-Amino-3-hydroxy-4-octadecen-1-yldihydrogenphosphat
[German]
[IUPAC name – generated by ACD/Name]
(4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate
26993-30-6
[RN]
4-Octadecene-1,3-diol, 2-amino-, 1-(dihydrogen phosphate), (4E)-
[IUPAC index name – generated by ACD/Name]
Dihydrogène phosphate de (4E)-2-amino-3-hydroxy-4-octadécèn-1-yle
Dihydrogénophosphate de (4E)-2-amino-3-hydroxy-4-octadécén-1-yle
[French]
[IUPAC name – generated by ACD/Name]
Sphingosine 1-phosphate
Sphingosine-1-phosphate
SMILES
CCCCCCCCCCCCC/C=C/C(O)C(N)COP(=O)(O)O
StdInChI
InChI=1S/C18H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h14-15,17-18,20H,2-13,16,19H2,1H3,(H2,21,22,23)/b15-14+
StdInChIKey
DUYSYHSSBDVJSM-CCEZHUSRSA-N
Molecular Formula
C18H38NO5P
Molecular Weight
379.478
MDL Number
MFCD00270077
Properties
Appearance
White to light yellow powder
Safety Data
Symbol
Signal Word
Warning
WGK Germany
3
MSDS Download
Specifications and Other Information of Our D-erythro-sphingosine-1-phosphate CAS 26993-30-6
Identification Methods
HNMR, HPLC
Purity
98% min
Shelf Life
1 year
Storage
Storage at -20°.
Known Application
1.Signal Molecule Research -Acts as a potent extracellular signaling lipid. -Binds to S1P receptors (S1PR1–5) and regulates cell migration, proliferation, differentiation, vascular development, and immune cell trafficking. 2. Pharmacological Research -Involved in immune regulation, cancer progression, cardiovascular diseases, and inflammation. -Basis for therapeutic development (e.g., Fingolimod/Gilenya®, an S1P receptor modulator for multiple sclerosis). 3. Research Reagent – Commonly used in cell signaling studies, lipid metabolism research, and immunology experiments. – Applied to study S1P-S1PR pathways in inflammation, tumor metastasis, and angiogenesis. 4. Potential Applications -Investigated as a drug target or tool compound for autoimmune diseases, atherosclerosis, asthma, and cancer therapy.
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Links
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